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Impact of Deep Marginal Elevation on Gum and Bone Health in Patients with Class II Dental Caries
Led by Tanta University · Updated on 2025-09-05
36
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the effects of the dental procedure called Deep Marginal Elevation DME on gum and bone health in patients with deep dental cavities, specifically Class II caries. This study aims to understand how DME influences inflammatory and microbiological markers in the periodontal environment, including the status of gingival tissues and bone levels. The research focuses on markers found in gingival fluid and bone changes seen through radiographic imaging to shed light on DMEs impact. The treatment involves elevating the deep margin of the cavity using resin-modified glass ionomer cement, followed by adhesive bonding and placement of a nanofilled composite restoration. This method helps improve access to the restoration margin and supports better sealing and plaque control. Participants will receive this single DME procedure as part of the study. During the study, gingival fluid samples will be collected to measure microbiological and inflammatory markers such as IL-1b2, TNF-b1, MMP-8, PGE2, and CRP. Radiographs will assess bone level, bone density, and crestal bone loss. Clinical evaluations including Gingival Index, Bleeding Index, and Clinical Attachment Loss will be performed. These assessments will take place one month after the intervention to monitor changes and safety. The total participation spans this follow-up period.
CONDITIONS
Brief Title
Deep Marginal Elevation and the Periodontal Microenvironment ( DME-PM )
Research Team
M
Mohamed O Elboraey, MD
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