Actively Recruiting
Development of a Radiomics Model Using 3T Multiparametric MRI to Predict Perilesional Infiltration of Musculoskeletal Tumors During Pre-Surgery Planning for Soft Tissue Sarcoma and Bone Cancer Tumors
Led by IRCCS Azienda Ospedaliero-Universitaria di Bologna · Updated on 2025-01-14
122
Participants Needed
1
Research Sites
187 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the use of radiomics, a technique analyzing MRI data, to detect tumor infiltration around suspected Bone Cancer Tumors or Soft Tissue Sarcomas (STS). The study aims to determine how accurately radiomics can identify participants truly diagnosed as positive and those who truly do not have the disease. This observational study focuses on participants suspected of these cancers who are preparing for surgical treatment. Participants will undergo MRI scans as part of their usual medical care, and their imaging data will be collected and analyzed anonymously using radiomics. The study does not add additional treatments or interventions beyond standard care. It focuses on assessing the potential clinical value of radiomics in pre-surgical planning by predicting tumor infiltration. During the study, researchers will track the positive and negative predictive values of the radiomics model from enrollment through two years of follow-up. Participants will not have additional procedures beyond their scheduled MRI scans, and their medical data will be monitored to evaluate the accuracy of this diagnostic approach. The total study participation lasts until the end of the two-year treatment period.
CONDITIONS
Official Title
Development of a Radiomics Model With MR to Predict the Occurence of a Infiltration of Muscoskeletal Tumor
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18
- Suspected soft tissue sarcoma with an indication for surgical treatment
- Suspected bone cancer tumor with an indication for surgical treatment
- Ability to give informed consent
You will not qualify if you...
- Current or past cancer within the last 5 years
- Serious acute or chronic conditions that could interfere with the study
- Contraindications to contrast-enhanced MRI including renal failure without dialysis, allergy to paramagnetic contrast agents, claustrophobia, symptomatic or history of epilepsy, cardiac pacemaker, incompatible implants, or pregnancy
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Trial Site Locations
Total: 1 location
1
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy, 40138
Actively Recruiting
Research Team
V
Vincenzo Lucidi, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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