Actively Recruiting
Dietary Impact on Sleep, Rhythms and Related Physiology
Led by Uppsala University · Updated on 2026-02-04
24
Participants Needed
1
Research Sites
118 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Sleep and metabolism are closely interconnected, and emerging evidence suggests that dietary composition may influence both sleep quality and key physiological functions such as glucose regulation, cardiovascular activity, and hormonal signaling. This study aims to investigate how a Western-style unhealthy diet versus a healthier, fiber-rich diet affects objective and subjective sleep measures, 24-hour physiological parameters, and a range of biomarkers related to cardiometabolic, neurodegenerative, and gut microbial function.
CONDITIONS
Official Title
Dietary Impact on Sleep, Rhythms and Related Physiology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-32 years
- Self-reported healthy and not on chronic medication
- BMI between 18 and 27 kg/m2 and waist circumference less than 102 cm
- Weight stable with less than 5% change in past 6 months
- Non-smoker and non-nicotine user
- Regular sleep-wake pattern with 7 to 9.25 hours of sleep per night
- Regular exercise habits for the last 2 months
- Regular daily meal pattern with three main meals
You will not qualify if you...
- Major or chronic illness such as diabetes, kidney disease, or inflammatory bowel disease
- Current or past endocrine or metabolic disorders
- Psychiatric or neurological disorders like bipolar disorder or epilepsy
- Frequent gastrointestinal symptoms
- Use of chronic medication
- Any sleep disorder including recent or chronic insomnia symptoms
- Shift work within the last three months or long-term shift work
- Extreme chronotype or unusual physical activity patterns
- Time travel across more than two time zones within the past month
- Weight gain or loss exceeding 5% in the past 6 months
- Allergies or issues with study-provided foods
- Recent major dietary changes or specific diet regimens
- Women who are pregnant, breastfeeding, or planning pregnancy during the study
- Use of illicit drugs or substances of abuse
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Uppsala biomedical center
Uppsala, Sweden, 75324
Actively Recruiting
Research Team
J
Jonathan Cedernaes, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
BASIC_SCIENCE
Number of Arms
2
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