Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT06258551

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients

Led by The Methodist Hospital Research Institute · Updated on 2024-02-14

1000

Participants Needed

2

Research Sites

285 weeks

Total Duration

On this page

Sponsors

T

The Methodist Hospital Research Institute

Lead Sponsor

N

National Institute of Allergy and Infectious Diseases (NIAID)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this observational study is to investigate how bacterial populations from the intestine and mouth of patients change during the hospitalization period and evaluate if some populations of specific bacteria increase or decrease the risk of acquiring an infection or becoming colonized by pathogenic bacteria. Participants will have the following samples collected during enrollment: stool samples (maximum 2x/week), blood draws (1x/week), oral swab (1x/week).

CONDITIONS

Official Title

Dynamics of Colonization and Infection by Multidrug-Resistant Pathogens in Immunocompromised and Critically Ill Patients

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Admission to an intensive care unit or stem cell transplant unit (for allogeneic stem cell transplantation) within previous 24 hours
Not Eligible

You will not qualify if you...

  • Under 18 years of age
  • Pregnancy
  • History of inflammatory bowel disease (Crohn's disease, ulcerative colitis)
  • Gastrointestinal derivation (colostomy, ileostomy, etc.)

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Houston Methodist Hospital

Houston, Texas, United States, 77030

Actively Recruiting

2

The University of Texas MD Anderson Cancer Center

Houston, Texas, United States, 77030

Actively Recruiting

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Research Team

C

Cesar A Arias, MD, PhD, Msc

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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