Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID06719063

Effect of Immersive Virtual Reality With Multisensory Stimulation on the Functional Impact of Hemineglect Secondary to a Right-Sided Stroke: A Single Case Experimental Design Study

Led by Hopital La Musse · Updated on 2025-05-11

3

Participants Needed

1

Research Sites

11 weeks

Total Duration

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AI-Summary

What this Trial Is About

Stroke is a common and serious condition, affecting many individuals each year and often leading to cognitive impairments such as hemineglect. Hemineglect causes difficulty responding to stimuli on one side, typically after a right hemisphere stroke, and often persists long-term, impacting daily function and rehabilitation outcomes. This research explores the use of immersive virtual reality combined with multisensory stimulation to reduce the functional effects of hemineglect in adults who have experienced a right-sided stroke within the past three months. The study involves a pilot design with repeated evaluation and rehabilitation sessions conducted in a hospital setting. Participants will undergo weekly assessments for 10 to 12 weeks using the Catherine Bergego Scale to measure how hemineglect affects autonomy. After an initial evaluation phase lasting 3 to 5 weeks, patients will receive three weekly 45-minute rehabilitation sessions over five weeks, including a 15-minute immersive virtual reality experience using the VirtySensae multisensory travel capsule. This capsule stimulates four senses simultaneously through visual, auditory, olfactory, and tactile inputs. During the study, participants will attend weekly evaluation sessions led by occupational therapists who will assess the impact of hemineglect and monitor tolerance to virtual reality. Rehabilitation sessions include review and explanation components, with a focus on patient comfort and response to the virtual reality treatment. The study aims to measure changes in autonomy, awareness of hemineglect, and the ability to tolerate the immersive environment over the 12-week period.

CONDITIONS

Brief Title

Effect of Immersive Virtual Reality With Multisensory Stimulation on the Functional Impact of Hemineglect Secondary to a Right-Sided Stroke

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient aged over 18 years
  • Diagnosed with first ischemic right stroke confirmed by clinical exam and brain imaging
  • Stroke occurred less than 3 months ago
  • Presence of left hemineglect diagnosed with the Neglect Assessment Battery
  • Normal vision or vision corrected to normal
  • Patient affiliated with the social security system
Not Eligible

You will not qualify if you...

  • History of neurological or psychiatric illness
  • Epilepsy
  • Craniotomy
  • Limited cervical motion due to orthopedic disorders
  • Moderate or severe deafness (40 dB hearing loss in one ear)
  • Anosmia (loss of smell)
  • Asthmatic disease
  • Pregnant or suspected pregnant women
  • Breastfeeding women
  • Severe neurocognitive disorders with MMSE score below 21
  • Patient under legal protection measures
  • Minor patients
  • Patient enrolled in another research protocol

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Baseline Evaluation

Duration - 3 to 5 weeks

Participants complete weekly evaluation sessions to measure the impact of hemineglect on autonomy using the Catherine Bergego Scale. These sessions also assess anosognosia and tolerance to immersive virtual reality.

Weekly visits for 3 to 5 weeks

Treatment

Duration - 5 weeks

Participants undergo three weekly rehabilitation sessions per week for 5 weeks. Each session lasts 45 minutes and includes a 15-minute multisensory immersive virtual reality experience designed for rehabilitation, with tolerance assessments after each session.

3 sessions per week for 5 weeks

Post-Treatment Evaluation

Duration - 2 to 4 weeks

Weekly evaluation sessions continue to measure the impact of hemineglect on autonomy, anosognosia, and tolerance to virtual reality after the treatment period.

Weekly visits for 2 to 4 weeks

Trial Site Locations

Total: 1 location

1

Hôpital La Musse

Saint-Sébastien-de-Morsent, France, 27180

Actively Recruiting

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Research Team

H

Héloïse BAILLET, PhD

J

Julie LE BALC'H

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

TREATMENT

Number of Arms

1

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