What is this study about the bond strength of zirconia resin-bonded dental prostheses?

This study is evaluating two different surface treatments for zirconia dental prostheses to see which one better helps the prosthesis stay attached in patients missing front teeth. Researchers want to find out if a new nanostructured alumina coating improves the bond compared to the usual method. The University of Ljubljana is sponsoring this research to improve dental restoration options.

Who may be eligible for this clinical trial involving missing incisors?

Adults and children with a missing central or lateral incisor may be eligible. Participants must have enough space for the prosthesis and healthy supporting teeth without active gum disease or infections. Those with teeth grinding or certain physical or psychological conditions may not qualify. Please review eligibility criteria for more details.

Is there any cost to participate in this dental prosthesis clinical trial?

Study-related care, including the prosthesis and all trial visits, is provided at no cost. However, personal travel expenses to attend visits may vary and are not guaranteed to be covered.

Actively Recruiting

Phase Not Applicable

All Genders

Healthy Volunteers

ID04693949

Study of Nanostructured Alumina Coating Versus Airborne Particle Abrasion on Bond Strength and Survival of Zirconia Resin-Bonded Dental Prostheses for Missing Central or Lateral Incisors

Led by University of Ljubljana, Faculty of Medicine · Updated on 2026-06-23

Participants Needed

Research Sites

156 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the clinical results of resin-bonded fixed dental prostheses RBFDPs that are treated with a nanostructured alumina coating NAC compared to the standard air-borne particle abrasion APA method. This study specifically focuses on patients needing replacement of missing central or lateral incisors. The goal is to determine which surface pretreatment method better supports the retention and survival of zirconia RBFDPs in a controlled, randomized, double-blind clinical trial. Participants receive zirconia RBFDPs with surfaces pretreated either by APA control group or by NAC experimental group after milling of the prostheses framework. Both groups are treated by the same operator, and neither participants nor operators know the group assignments to maintain blinding. The study monitors the prostheses retention and survival rates, comparing the two pretreatment methods over time. During the study, participants undergo regular evaluations for up to one year to assess the prostheses survival and check for complications such as porcelain chipping, zirconia framework fractures, gingivitis, periodontitis, marginal leakage, and secondary caries. These assessments involve clinical examination and monitoring by dentists. The study aims to provide detailed data on the durability and clinical success of zirconia RBFDPs treated with NAC versus APA over the follow-up period.

CONDITIONS

Brief Title

Effect of Nano-structured Alumina Coating on the Bond Strength of Zirconia Resin-bonded Fixed Dental Prostheses

Who Can Participate

All Genders

Healthy Volunteers

Eligibility Criteria

You may qualify if you...

Patients with missing central or lateral incisor

You will not qualify if you...

Inadequate edentulous space for the pontic
Signs of bruxism
Abutment tooth with active periodontal or periapical disease
Inadequate enamel bonding surface of the abutment tooth
Inadequate interocclusal space for a retainer wing and a proximal connector
Pontic guidance
Physical or psychological disease likely to interfere with normal conduct of the study

Research Team

Tine Malgaj, DMD

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