Actively Recruiting

Phase Not Applicable
Age: 0 - 21Years
All Genders
NCT04504227

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

Led by Boston Children's Hospital · Updated on 2026-03-18

200

Participants Needed

1

Research Sites

282 weeks

Total Duration

On this page

Sponsors

B

Boston Children's Hospital

Lead Sponsor

N

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This study will examine the effects of varying liquid viscosity on swallow physiology in infants with oropharyngeal dysphagia and brief resolved unexplained event (BRUE) and other children with dysphagia that would be at risk for symptoms of swallow dysfunction.

CONDITIONS

Official Title

Effect of Thickened Feeds on Swallow Physiology in Children With Dysphagia

Who Can Participate

Age: 0 - 21Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 0 to 21 years
  • Admitted to Boston Children's Hospital after first lifetime brief resolved unexplained event (BRUE), or with dysphagia symptoms putting them at risk for BRUE or swallowing difficulties
  • Have had or might have videofluoroscopic swallow study performed
Not Eligible

You will not qualify if you...

  • Pre-existing diagnoses excluding BRUE such as seizure disorders or cyanotic congenital heart disease
  • Nasal, pharyngeal, or esophageal anomalies affecting safe placement of pharyngeal motility catheter
  • Children fed only by enteral tube
  • Allergy to rice cereal or Gelmix thickener

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Boston Children's Hospital

Boston, Massachusetts, United States, 02115

Actively Recruiting

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Research Team

D

Daniel R Duncan, MD, MPH

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

DIAGNOSTIC

Number of Arms

4

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