Actively Recruiting

Age: 18Years +
All Genders
NCT06163131

The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility

Led by Aarhus University Hospital · Updated on 2023-12-08

35

Participants Needed

1

Research Sites

174 weeks

Total Duration

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AI-Summary

What this Trial Is About

In some patients with chronic obstructive pulmonary disease (COPD) the breathlessness is caused by hyperinflation of the lungs. This causes difficulty breathing air out and makes it harder to breath in new air and limits the movement of the diaphram. The diaphragm is the muscle used for breathing between the chest and the stomach. Some of these patients can receive treatment with endobronchial valves, where one-ways are inserted into the bronchial system the let out some of the excess air, and thereby relieve breathlessness. The goal of this observational study is to investigate the effect of endobronchial valves on the mobility of the diaphragm in patients with chronic obstructive pulmonary disease. The main questions it aims to answer are: * If the movement of the diaphragm improves after treatment with endobronchial valves. * If there is a link between improvement of diaphragm function and improvement of symptoms, lung function and physical ability. * If ultrasound scan immediately after the treatment will predict which patients will benefit from the treatment. Participants will undergo ultrasound before, 1 day after and 90 days after the procedure, and lung function examinations from their already planned control visits will be collected.

CONDITIONS

Official Title

The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients selected to receive treatment with endobronchial valves
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • Neuromuscular disease interfering with diaphragm function
  • Pleural effusion at time of preoperative or 90-days postoperative ultrasound

AI-Screening

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Trial Site Locations

Total: 1 location

1

Aarhus University Hospital

Aarhus, Denmark, 8200

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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The Effect of Treatment of Emphysema With Endobronchial Valves on the Diaphragm Mobility | DecenTrialz