Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT07274631

A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine

Led by CHU de Reims · Updated on 2026-02-20

470

Participants Needed

1

Research Sites

782 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Chronic inflammatory pulmonary diseases, including asthma, chronic obstructive pulmonary disease (COPD), bronchiectasis, cystic fibrosis (CF), primary ciliary dyskinesia (PCD) and interstitial lung diseases (ILD) are characterised by lung inflammation and remodelling. Clinical, functional, microbiological, biological, pathological and prognostic features are highly variable and heterogeneous. Several phenotypes have been described within the same pathology, as similar phenotypic traits between different pathologies, or the coexistence of components of several diagnoses in the same patient, suggesting shared underlying mechanisms that could represent new therapeutic targets, beyond the initial medical diagnosis. The objectives of this prospective study are to analyze the phenotypic characteristics (clinical, demographic, biological, morphological, pathological, and microbiological characteristics) together with respiratory exposures and underlying mechanisms involving airway epithelium and inflammation processes in a cohort of patients diagnosed with asthma, COPD, bronchiectasis, CF, PCD and ILD.

CONDITIONS

Official Title

A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Diagnosis of asthma, COPD, bronchiectasis, cystic fibrosis, primary ciliary dyskinesia, or interstitial lung diseases
  • Healthy volunteers with no respiratory diseases
Not Eligible

You will not qualify if you...

  • Individuals legally protected by law (e.g., legal incapacity)
  • Any condition that prevents giving informed consent or participating in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chu Reims

Reims, France, 51092

Actively Recruiting

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Research Team

J

Jeanne-Marie PEROTIN-COLLARD

CONTACT

G

Gaëtan DESLEE

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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A Cohort for Inflammatory Respiratory Diseases: From Phenotyping to Personalised Medicine | DecenTrialz