Study of How Steep Trendelenburg Position and Pneumoperitoneum Affect Optic Nerve Sheath Diameter During Robot-Assisted and Open Radical Prostatectomy

What this Trial Is About

This research aims to evaluate how the steep Trendelenburg position and pneumoperitoneum affect the optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic radical prostatectomy compared to open radical prostatectomy. The study focuses on patients with prostate cancer and investigates how these surgical conditions might increase intracranial pressure during general anesthesia. Optic nerve sheath diameter is measured noninvasively using ocular ultrasonography to assess these pressure changes. Participants are divided into two groups those having robot-assisted laparoscopic prostatectomy and those having open radical prostatectomy, both under general anesthesia. During surgery, optic nerve sheath diameter will be measured at set times, and other factors such as hemodynamic and respiratory parameters, intra-abdominal pressure, surgery duration, blood loss, and fluids given will be recorded to understand physiological changes. Patients will be carefully monitored throughout the surgery with ultrasound and other measures to track changes in intracranial pressure and related parameters. The main outcome measured is the optic nerve sheath diameter at specific intraoperative time points. This observational study is led by Ege University and will run until September 2026, with participants involved during their surgical procedure and data collection at those times.

Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted Prostatectomy