Actively Recruiting
The Effect of the Valsalva Maneuver in Endometrial Biopsy: A Randomized Controlled Trial
Led by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · Updated on 2026-03-27
120
Participants Needed
1
Research Sites
99 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Endometrial sampling with a pipelle is a common procedure used to collect a small sample from the lining of the uterus. During the procedure, the cervix is sometimes held with a surgical instrument called a tenaculum, which may cause pain and anxiety for some women. The Valsalva maneuver is a simple technique in which a person takes a deep breath and pushes as if trying to exhale forcefully. This increases pressure inside the abdomen and may help keep the uterus and cervix more stable during the procedure. This study aims to compare pipelle sampling performed with the Valsalva maneuver to the standard method using a tenaculum. The study will evaluate whether the Valsalva maneuver can reduce pain and anxiety while maintaining procedure success and improving patient satisfaction.
CONDITIONS
Official Title
The Effect of the Valsalva Maneuver in Endometrial Biopsy: A Randomized Controlled Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Endometrial sampling indication in reproductive age group of patients over 18 years of age, who can communicate in Turkish.
You will not qualify if you...
- Patients under 18 years of age
- Postmenopausal patients
- Pregnancy
- Patients with known stenotic cervical os
- Patients with a history of acute cervicitis
- Patients with intense anxiety
- Need for simultaneous endocervical curettage
- Need for general or local anesthesia
- Having used analgesic medication before the procedure
- History of a known malignancy, uterine anomaly, or leiomyoma affecting the cervical canal or uterine cavity, or uterine prolapse
- Patients with known chronic pelvic pain
AI-Screening
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Trial Site Locations
Total: 1 location
1
Cemil Tascioglu City Hospital
Istanbul, Turkey (Türkiye)
Actively Recruiting
Research Team
N
Neslihan Doctor
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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