Actively Recruiting

Phase Not Applicable
Age: 20Years +
All Genders
Healthy Volunteers
NCT04243226

Effects of Aerobic Exercise on Cognition,cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients

Led by National Defense Medical Center, Taiwan · Updated on 2025-02-14

120

Participants Needed

1

Research Sites

347 weeks

Total Duration

On this page

Sponsors

N

National Defense Medical Center, Taiwan

Lead Sponsor

M

Ministry of Science and Technology, Taiwan

Collaborating Sponsor

AI-Summary

What this Trial Is About

The aim of this study is to develop exercise prescription of TBI patients and then to evaluate the effectiveness of programmed aerobic walking exercise to improve cognitive performance, depression relief, motivation, symptom, resilience and quality of life with improvement of CBF. This will be a randomized controlled clinical trial, using a mixed method to explore the feasibility and validity of such a safety exercise prescription. Then, a randomized clinical control trial will be applied in TBI patients to evaluate the effectiveness of programmed aerobic exercise to promote psysical-psycho-social health such as cognitive status, 6 minutes walk test, depression relief, motivation, symptom, resilience and quality of life.

CONDITIONS

Official Title

Effects of Aerobic Exercise on Cognition,cerebral Brain Flow and Mental Health Among Traumatic Brain Injury Patients

Who Can Participate

Age: 20Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed with mild traumatic brain injury at the emergency department
  • Glasgow Coma Scale (GCS) score of 14-15 at emergency or moderate brain injury with GCS score of 8-13
  • More than three months since discharge from hospital after brain injury
  • Able to communicate in Chinese or Taiwanese
  • Good audio-visual ability to complete tests and data entry
  • Willing to sign consent form to participate
  • Able to walk independently, communicate freely, and live in Taipei or Greater Taipei area
Not Eligible

You will not qualify if you...

  • Severe cognitive, emotional, or executive function impairment due to prefrontal lobe injury
  • Brain injury caused by head puncture
  • Regularly performing moderate-intensity aerobic exercise

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

TSGH

Taipei, Taiwan

Actively Recruiting

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Research Team

H

Hui-Hsun Chiang, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

2

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