Evaluating Controlled Breathing Added to Therapeutic Exercise in Adults with Multiple Myeloma to Improve Symptoms and Quality of Life

What This Trial Is About

Researchers are evaluating the addition of a controlled breathing exercise program to a therapeutic exercise intervention in adults with multiple myeloma. This randomized, double-blind clinical trial compares two groups over a 6-week period to determine the impact on somatic symptoms and other related health factors. The study aims to improve understanding of how breathing exercises may influence quality of life and symptom management in this population. Participants are assigned randomly to one of two groups. Both groups receive a therapeutic exercise program plus an initial educational session on proper breathing. One group additionally performs a home-based controlled breathing exercise protocol twice daily at home. The exercise program involves three weekly sessions of mobility and muscle-strengthening exercises two on-site and one home-based and walking at least 7,000 steps or 50 minutes three days per week. The breathing exercises are guided by audio recordings through a web app. Participants are assessed before starting, at the end of the 6-week intervention, and again 4 weeks later. Researchers will measure somatic symptoms, quality of life, sleep quality, fatigue, anxiety, and depression using questionnaires and scales. Adherence to exercise and breathing protocols is monitored via a smartphone app. The total study involvement lasts approximately 10 weeks including follow-up, with ongoing clinical monitoring throughout.

Effects of Controlled Breathing Added to Therapeutic Exercise in Multiple Myeloma