Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07034599

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.

Led by Karlsburg Hospital · Updated on 2026-02-18

30

Participants Needed

1

Research Sites

60 weeks

Total Duration

On this page

Sponsors

K

Karlsburg Hospital

Lead Sponsor

U

University Hospital Freiburg

Collaborating Sponsor

AI-Summary

What this Trial Is About

All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.

CONDITIONS

Official Title

Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • All patients after implantation of a durable left ventricular assist device
Not Eligible

You will not qualify if you...

  • Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Klinikum Karlsburg

Karlsburg, Germany

Actively Recruiting

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Research Team

M

Matthias Heringlake, Prof. Dr. med.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

1

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Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device. | DecenTrialz