Actively Recruiting
A Single Day of Inactivity on the Systemic Metabolic and Inflammatory Exercise Response
Led by Concordia University Wisconsin · Updated on 2026-02-24
6
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how a single day of reduced physical activity affects the body's response to aerobic exercise. It focuses on how inactivity influences metabolism, inflammation, and immune pathways, which may alter the benefits typically gained from exercise. The study seeks to analyze changes in circulating metabolites and proteins after exercise following a day of low activity. Participants will be assigned randomly to one of two groups: one group will walk less than 5,000 steps the day before exercise (reduced activity), and the other will walk more than 8,500 steps (active comparison). The study evaluates the metabolic and inflammatory responses to exercise under these different activity conditions. During the study, participants will complete assessments within six weeks of enrollment. Researchers will measure the concentration of metabolites and proteins in plasma to understand systemic changes caused by inactivity. The study includes monitoring participant activity levels and collecting biological samples to evaluate exercise response, with a focus on metabolic and inflammatory markers.
CONDITIONS
Brief Title
The Effects of One Day of Activity on the Next Day's Exercise Response
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Between the ages of 18 and 30 years old
You will not qualify if you...
- Free from acute or chronic illness including cardiac, pulmonary, liver, or kidney abnormalities, cancer, uncontrolled hypertension, insulin- or non-insulin dependent diabetes, or other known metabolic disorders
- Not taking medications related to metabolism such as statins, metformin, or GLP-1 agonists
- Free from orthopedic limitations including any artificial joints
- Do not currently smoke or use any form of tobacco
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 6 weeks
Participants will complete days of differing step counts followed by exercise testing to analyze metabolic and inflammatory responses.
Multiple visits depending on crossover schedule
Trial Site Locations
Total: 1 location
1
Concordia University of Wisconsin
Mequon, Wisconsin, United States, 53093
Actively Recruiting
Research Team
K
Kevin J Gries, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
PREVENTION
Number of Arms
2
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