Study of Daily Transcranial Current Stimulation Treatment for Adults With Psychophysiological Insomnia

What this Trial Is About

Researchers are investigating the effects of transcranial current stimulation on insomnia disorder, a common sleep problem. This study aims to understand how this noninvasive device impacts brain activity and neurobiological changes related to sleep. Although this treatment is promising, its specific effects on brain structure and function during sleep are still unclear. Participants will receive either active or sham transcranial current stimulation for 14 consecutive days. Each session lasts 20 minutes with a 1.1-mA current, including 30 seconds of gradual current changes at the start and end. The sham group will wear the device without any stimulation. The study is randomized and quadruple-blinded to compare the outcomes between these two groups. During the study, participants will be assessed at 2 weeks and 3 months after treatment. Researchers will measure brain blood flow signals, brain connectivity, and other brain activity markers using imaging techniques. They will also evaluate insomnia severity, anxiety, depression, sleep quality through polysomnography, and biological factors such as hormone and protein levels in the blood. This comprehensive monitoring will help understand the treatments effects and safety over time.

The Effects of Transcranial Current Stimulation on Insomnia