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Efficacy of Biofeedback Training for Visual Function and Quality of Life in Glaucoma: A Randomized Controlled Trial
Led by University Health Network, Toronto · Updated on 2026-02-13
70
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effects of visual biofeedback training on visual function and quality of life in people with glaucoma, a condition that causes progressive optic nerve damage leading to vision loss. This trial aims to see if biofeedback training can improve fixation stability and help patients use their remaining vision more effectively. The study includes 70 participants diagnosed with glaucoma who have stable intraocular pressure and specific visual field impairments near the center of vision. Participants will be randomly assigned to one of two groups: a biofeedback training group or a control group. Those in the biofeedback group will receive five weekly sessions of training lasting about 20 minutes each, where they will use visual and auditory feedback to guide their eye movements toward retinal areas with better sensitivity. The control group will have standard clinical assessments and will be offered biofeedback training after completing the control period. Participants will undergo various assessments at the start of the study and at follow-up visits including 9 weeks, 6 months, 1 year, and up to 2 years after the intervention. These assessments include measuring fixation stability, retinal sensitivity, visual acuity, reading speed, contrast sensitivity, and quality of life. The study will monitor changes over time to determine if biofeedback training can improve functional vision and life quality in glaucoma patients.
CONDITIONS
Brief Title
Efficacy of Biofeedback Training for Glaucoma
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 95 years old
- Diagnosis of glaucoma with adequate intraocular pressure control
- Presence of paracentral scotomata within two degrees of fixation
- Ability to follow instructions for biofeedback training
You will not qualify if you...
- Prior or current low vision rehabilitation treatment
- Ocular diseases or severe clinical conditions unrelated to glaucoma
- Media opacities preventing reliable microperimetry testing in both eyes
- Inability to perform study assessments or follow instructions for biofeedback training
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 5 weeks
Participants randomized to the training group undergo five weekly sessions of visual biofeedback training. Each session lasts approximately 20 minutes, using visual and auditory feedback to improve eye movement control and optimize residual vision.
5 weekly visits (in-person)
Duration - Up to 2 years post-intervention
Participants complete visual function and quality of life assessments at multiple timepoints after training or control period to evaluate the effects of the intervention.
Visits at 9 weeks, 6 months, 1 year, and 2 years post-intervention
Trial Site Locations
Total: 1 location
1
University Health Network/ Toronto Western Hospital
Toronto, Ontario, Canada, M5T 2S8
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
SUPPORTIVE_CARE
Number of Arms
2
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