Trial Comparing Ejaculation-Preserving and Standard Bipolar Transurethral Enucleation of the Prostate in Men With Benign Prostatic Hyperplasia and Urinary Symptoms

What this Trial Is About

This research aims to compare two surgical methods for treating benign prostatic hyperplasia BPH in sexually active men who have lower urinary tract symptoms and have not improved with medical treatment. It evaluates whether a new ejaculation-preserving bipolar transurethral enucleation of the prostate technique can maintain ejaculatory function while still relieving urinary symptoms. The trial also looks at erectile function, urinary flow, residual urine after urination, complications around surgery, and the need for further treatment. Participants will be randomly assigned to receive either the ejaculation-preserving bipolar transurethral enucleation of the prostate, which preserves specific prostate tissues near the verumontanum to protect ejaculation, or the standard bipolar transurethral enucleation without these modifications. Both procedures are surgical techniques performed endoscopically. The study compares these two approaches to assess their effects on sexual and urinary function over time. During the study, men will be assessed before and after surgery using questionnaires on sexual and urinary function, as well as objective urinary tests such as uroflowmetry and measurements of post-void residual urine. Follow-up will focus on changes in ejaculatory function, erectile function, symptom scores, surgical complications, and retreatment rates. The main outcome is the change in ejaculatory function score from baseline to six months after surgery, with additional assessments made at the same intervals.

Ejaculation-Preserving Versus Standard Bipolar TUEP for BPH