Actively Recruiting

Early Phase 1
Age: 21Years - 80Years
All Genders
Healthy Volunteers
NCT07531264

EMG-guided Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction

Led by University of Houston · Updated on 2026-04-15

48

Participants Needed

1

Research Sites

355 weeks

Total Duration

On this page

Sponsors

U

University of Houston

Lead Sponsor

T

TIRR Memorial Hermann

Collaborating Sponsor

AI-Summary

What this Trial Is About

The objective of this study is to develop Neuro-Intermuscular Coordination Enhancement (NICE) rehabilitation, a novel neuromuscular control signal-guided strategy that visually guides stroke patients to individually activate groups of synergistic muscles through human-machine interaction. Ultimately, the development will lead to better clinical motor recovery, better quality of life, and lowered healthcare costs associated with the impairment.

CONDITIONS

Official Title

EMG-guided Neuro-Intermuscular Coordination Enhancement (NICE) Rehabilitation Through Human-Machine Interaction

Who Can Participate

Age: 21Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Experienced ischemic or hemorrhagic stroke
  • Between 21 and 80 years old
  • No botulinum toxin treatment on impaired arm within last 3 months
  • Modified Ashworth Scale (MAS) score less than or equal to 3 around elbow and shoulder
Not Eligible

You will not qualify if you...

  • Orthopedic disorder involving upper limbs
  • Cognitive impairment interfering with consent or study completion (MoCA score less than 26)
  • History of other neurological diseases
  • Loss of joint position sense in upper limbs
  • Pregnant or possibly pregnant (self-reported)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Houston

Houston, Texas, United States, 77045

Actively Recruiting

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Research Team

J

Jinsook Roh, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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