Actively Recruiting

Phase Not Applicable
Age: 18Years - 30Years
All Genders
Healthy Volunteers
NCT06866028

Enhancing Emotion Regulation Through Functional Near-infrared Spectroscopy (fNIRS)-Informed Real-time Neurofeedback

Led by University of Electronic Science and Technology of China · Updated on 2025-03-27

50

Participants Needed

1

Research Sites

104 weeks

Total Duration

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AI-Summary

What this Trial Is About

The present study aims to employ real-time functional near-infrared spectroscopy (fNIRS) neurofeedback training in combination with cognitive reappraisal strategies for regulating negative emotions in healthy individuals. Participants will complete: * Cognitive reappraisal training with either real neurofeedback or sham feedback. * Questionnaires at pre- and post- training timepoints * A cold-pressor test at the end of the training It is hypothesized that combining real-time fNIRS neurofeedback and cognitive reappraisal training will enhance emotion regulation in healthy individuals: 1. Increased neural activity in the prefrontal cortex (PFC) region of the brain will be significantly higher in the real neurofeedback group after training compared to the sham feedback group. 2. Real-time fNIRS-guided upregulation of the PFC will enhance emotion regulation during exposure to negative stimuli/scenes across the training runs. 3. The effects of fNIRS neurofeedback training will extend to influence emotion regulation in a cold-pressor test administered post-training, wherein individuals in the real neurofeedback group demonstrate better regulation of stress and pain induced by the task.

CONDITIONS

Official Title

Enhancing Emotion Regulation Through Functional Near-infrared Spectroscopy (fNIRS)-Informed Real-time Neurofeedback

Who Can Participate

Age: 18Years - 30Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Normal or corrected-to-normal vision
  • Right-handed
  • Beck Depression Inventory (BDI-II) score below 29 indicating no clinically significant depression
Not Eligible

You will not qualify if you...

  • Current or past history of mental health conditions
  • Current or past history of chronic pain
  • Cardiovascular disorder
  • Raynaud's phenomenon
  • Fainting
  • Seizures
  • Wounds on the hand or arm
  • Frequent use of alcohol or nicotine

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Hong Kong Jockey Club Building For Interdisciplinary Research, 5 Sassoon Rd, Sandy Bay

Hong Kong, Hong Kong

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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