Study of Live and Recorded Music Effects on Stress, Mood, Pain, and Biomarkers in Neurosurgery Patients

What this Trial Is About

This research aims to evaluate the effects of live and recorded music-based interventions on pre-operative stress, mood, pain, and related biomarkers in patients undergoing neurosurgery. The study focuses on measuring changes in vital signs, serum and plasma stress biomarkers, cytokines, as well as perceived anxiety, mood, and pain using validated questionnaires. Additionally, the study investigates correlations between demographic factors, prior musical experience, preference, and exposure to music with stress reduction. Participants will be randomly assigned to one of three groups simulated live music, recorded music, or a control group with no music. The music interventions will be applied before surgery using a Steinway Spirio M recordingplayer piano. The study uses a randomized design with equal allocation to each group to compare the physiological and psychological effects of these interventions. During the study, participants will have their vital signs and blood samples collected for biomarker analysis before and after the music intervention. They will also complete questionnaires assessing anxiety, mood, pain, and musical experience. Researchers will analyze changes throughout the study to assess stress and mood alterations as well as biomarker responses. The total participation duration spans until study completion, with ongoing monitoring of stress and mood changes and music experience questionnaire data.

A Randomized Controlled Trial to Assess the Impact of Live and Recorded Music-Based Interventions on Pre-operative Stress, Mood, Pain and Biomarkers, in Neurosurgical Patients (Music-STAR Trial)