Actively Recruiting
Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in Chronic Obstructive Pulmonary Disease
Led by China-Japan Friendship Hospital · Updated on 2025-02-10
30
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are investigating the ability to grow human lung stem cells in the lab and create lung organoids derived from patients with Chronic Obstructive Pulmonary Disease (COPD). The study aims to answer whether human lung stem cells can multiply in vitro and if lung organoids from COPD patients can be successfully established. Participants will be sampled during a pulmonary bronchoscopy procedure. Participants in this observational study are patients with COPD who will undergo bronchoscopy to collect samples for lung stem cell and organoid research. There are no experimental treatments or drugs being given, as the study focuses on sample collection during standard medical procedures. During the study, participants will have the number of patients completing bronchoscopy recorded as the main outcome measure. The study involves a single day of bronchoscopy sampling, with no additional interventions or long-term follow-up specified. Researchers will monitor the success of lung stem cell proliferation and organoid construction from the collected samples.
CONDITIONS
Brief Title
Establishment of Human Lung Stem Cell Proliferation System and Organoid Construction in COPD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age under 55, regardless of gender
- Patients with COPD lung disease who are going to undergo bronchoscopic biopsy
- No genetic diseases and other respiratory diseases
You will not qualify if you...
- Conditions making sampling or follow-up difficult
- Presence of other serious diseases
- Other conditions deemed unsuitable by investigators for inclusion
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants with COPD undergo bronchoscopic biopsy to collect lung samples.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
China-Japan Friendship Hospital
Beijing, Beijing Municipality, China, 100029
Actively Recruiting
Research Team
M
Mingming Deng, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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