Actively Recruiting

Phase Not Applicable
Age: 18Years - 26Years
All Genders
NCT06302296

Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement

Led by Hama University · Updated on 2025-09-15

14

Participants Needed

1

Research Sites

29 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

One of the main goals of orthodontic treatment is the reduction of treatment time through faster tooth movement. The previous studies evaluating platelet-rich fibrin (PRF) and orthodontic tooth movement (OTM) are limited, which makes the results difficult to generalize.

CONDITIONS

Official Title

Evaluating the Effect of Injectable Platelet-rich Fibrin on Accelerating Orthodontic Tooth Movement

Who Can Participate

Age: 18Years - 26Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 26 years
  • Severe irregularity of upper incisors greater than 7 mm needing first premolar extraction
  • Class I or Class II malocclusion with skeletal Class I or II and normal or mild vertical growth
  • All permanent upper teeth up to the first molar present and suitable for bracket placement
  • Good oral health
Not Eligible

You will not qualify if you...

  • Presence of systemic diseases affecting orthodontic tooth movement
  • Severe malalignment of specific teeth like palatal quadrant, ectopic canine, or ectopic premolar
  • Previous orthodontic treatment
  • Use of medications affecting tooth movement such as cortisone or non-steroidal anti-inflammatory drugs
  • Poor oral health
  • Inability to commit to regular follow-up appointments

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fadi Jnaid

Hama, Syria

Actively Recruiting

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Research Team

F

FADI JNAID, Associate Professor

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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