Actively Recruiting

Age: 18Years +
All Genders
NCT06542016

An Evaluation of the KCCQ Score in Predicting Cardiovascular Risk in Dialysis Patients

Led by Shenzhen Second People's Hospital · Updated on 2024-08-07

136

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Cardiovascular Disease (CVD) is the main complication and the most important cause of death in CKD patients. As the disease progresses, the incidence of cardiovascular disease in CKD patients gradually increases, especially in End-Stage Renal Disease (ESRD) patients receiving dialysis treatment, where the prevalence of cardiovascular disease reaches its highest level. Currently, there is a lack of a simple and reliable tool to assess the cardiac function status and predict the risk of cardiovascular events in patients on maintenance dialysis. The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a widely used patient-reported outcomes measurement tool for assessing health-related quality of life in heart failure patients. It has been shown that KCCQ scores not only reflect the underlying undiagnosed symptoms of heart failure in CKD patients, but also have a strong correlation with prognosis. However, there is currently insufficient clinical evidence to confirm the value of the KCCQ in patients on maintenance dialysis. Investigators will perform a prospective, single-center, observational study to collect the changing trend of KCCQ scores at baseline and during the observation periods in maintenance dialysis patients, to analyze the association between the scores and the occurrence of long-term cardiovascular events and all-cause mortality. The aim is to construct a predictive model of KCCQ scores to provide a reference basis for clinical management of this high-risk group, so as to optimize the diagnosis and treatment of heart failure in dialysis patients and improve their cardiovascular outcomes.

CONDITIONS

Official Title

An Evaluation of the KCCQ Score in Predicting Cardiovascular Risk in Dialysis Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older with no gender or ethnicity restrictions
  • Diagnosis of stage 5 chronic kidney disease according to KDOQI guidelines
  • Newly diagnosed uremia patients planning to start maintenance dialysis or patients currently on maintenance dialysis (hemodialysis or peritoneal dialysis)
  • Clear contact information for patient or family to allow follow-up
  • Signed informed consent and ability to complete the KCCQ questionnaire
Not Eligible

You will not qualify if you...

  • Acute kidney injury from any cause
  • Severe mental illness affecting ability to complete questionnaires
  • Acute myocardial infarction, coronary artery stent implantation, coronary artery bypass grafting, or pacemaker implantation within the past three months
  • Special heart diseases such as cardiac amyloidosis, congenital heart disease, or pericardial diseases
  • Chronic lung diseases
  • Serious underlying diseases such as severe infections, tumors, or severe liver diseases
  • Scheduled for kidney transplantation

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

First Shenzhen

Guangdong, Guangdong, China, 518000

Actively Recruiting

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Research Team

Y

Yi Xu

CONTACT

J

Jiafang Li

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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