Actively Recruiting
An Evaluation of the KCCQ Score in Predicting Cardiovascular Risk in Dialysis Patients
Led by Shenzhen Second People's Hospital · Updated on 2024-08-07
136
Participants Needed
1
Research Sites
104 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cardiovascular Disease (CVD) is the main complication and the most important cause of death in CKD patients. As the disease progresses, the incidence of cardiovascular disease in CKD patients gradually increases, especially in End-Stage Renal Disease (ESRD) patients receiving dialysis treatment, where the prevalence of cardiovascular disease reaches its highest level. Currently, there is a lack of a simple and reliable tool to assess the cardiac function status and predict the risk of cardiovascular events in patients on maintenance dialysis. The Kansas City Cardiomyopathy Questionnaire (KCCQ) is a widely used patient-reported outcomes measurement tool for assessing health-related quality of life in heart failure patients. It has been shown that KCCQ scores not only reflect the underlying undiagnosed symptoms of heart failure in CKD patients, but also have a strong correlation with prognosis. However, there is currently insufficient clinical evidence to confirm the value of the KCCQ in patients on maintenance dialysis. Investigators will perform a prospective, single-center, observational study to collect the changing trend of KCCQ scores at baseline and during the observation periods in maintenance dialysis patients, to analyze the association between the scores and the occurrence of long-term cardiovascular events and all-cause mortality. The aim is to construct a predictive model of KCCQ scores to provide a reference basis for clinical management of this high-risk group, so as to optimize the diagnosis and treatment of heart failure in dialysis patients and improve their cardiovascular outcomes.
CONDITIONS
Official Title
An Evaluation of the KCCQ Score in Predicting Cardiovascular Risk in Dialysis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 or older with no gender or ethnicity restrictions
- Diagnosis of stage 5 chronic kidney disease according to KDOQI guidelines
- Newly diagnosed uremia patients planning to start maintenance dialysis or patients currently on maintenance dialysis (hemodialysis or peritoneal dialysis)
- Clear contact information for patient or family to allow follow-up
- Signed informed consent and ability to complete the KCCQ questionnaire
You will not qualify if you...
- Acute kidney injury from any cause
- Severe mental illness affecting ability to complete questionnaires
- Acute myocardial infarction, coronary artery stent implantation, coronary artery bypass grafting, or pacemaker implantation within the past three months
- Special heart diseases such as cardiac amyloidosis, congenital heart disease, or pericardial diseases
- Chronic lung diseases
- Serious underlying diseases such as severe infections, tumors, or severe liver diseases
- Scheduled for kidney transplantation
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
First Shenzhen
Guangdong, Guangdong, China, 518000
Actively Recruiting
Research Team
Y
Yi Xu
CONTACT
J
Jiafang Li
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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