Actively Recruiting

Phase Not Applicable
Age: 4Years - 9Years
All Genders
Healthy Volunteers
NCT03713125

Executive Function in Early Childhood

Led by Vanderbilt University · Updated on 2025-08-14

260

Participants Needed

1

Research Sites

363 weeks

Total Duration

On this page

Sponsors

V

Vanderbilt University

Lead Sponsor

E

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Despite the fact that a substantial number of school age children struggle with both reading and math acquisition, the brain mechanisms of the overlapping aspects of reading and math skills, thought in part to be linked via executive functions (EF), have not been unpacked. This project will use a longitudinal design, following children from Kindergarten through 1st grade, to understand how the brain networks associated with reading, math, and EF interact to predict academic outcomes and, in those who struggle academically, intervention response.

CONDITIONS

Official Title

Executive Function in Early Childhood

Who Can Participate

Age: 4Years - 9Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Children in Kindergarten (approximate ages 4-9 years)
  • Native English speakers
Not Eligible

You will not qualify if you...

  • Not in Kindergarten at time of enrollment
  • Previous diagnosis of Intellectual Disability
  • Known uncorrectable visual impairment
  • Hearing impairment of 25 decibels or greater
  • Medical contraindications to MRI procedures, such as metal devices (excludes only from MRI)
  • Known IQ below 70
  • Pervasive developmental disorder
  • Known neurologic pathology including epilepsy, spina bifida, cerebral palsy, traumatic brain injury, brain tumors
  • Severe psychiatric disorders or use of psychotropic medications (except stimulant medication for ADHD)
  • Taking psychotropic medications other than stimulant medication for ADHD

AI-Screening

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Trial Site Locations

Total: 1 location

1

Vanderbilt University

Nashville, Tennessee, United States, 37240

Actively Recruiting

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Research Team

J

Julie Delheimer, BS

CONTACT

L

Lanier P Sachs, M.Ed.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

OTHER

Number of Arms

2

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