Actively Recruiting
Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome
Led by Queen's Medical Center · Updated on 2026-02-20
22
Participants Needed
1
Research Sites
158 weeks
Total Duration
On this page
Sponsors
Q
Queen's Medical Center
Lead Sponsor
U
University of Hawaii Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
This project aims to investigate if the contraceptive method, Phexxi, causes changes to the composition of the vaginal microbiome. The investigators hypothesize that regular use of Phexxi will cause increased colonization of lactic acid-producing lactobacilli, which could have positive effects in the way of preventing recurrent episodes of BV and candida infections.
CONDITIONS
Official Title
Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal Microbiome
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18-54
- Female
- Pre-menopausal
- Can speak and read in English
- Displays capacity for informed consent
- Has had 2 or more documented and/or self-reported episodes of symptomatic BV or candida infection in the last year, requiring, over-the-counter or prescription treatment
You will not qualify if you...
- Pregnant or trying to become pregnant
- Post-menopausal
- Using NuvaRing device
- A past medical history of kidney disease, recurrent UTI, and/or urinary tract abnormalities
- Current UTI
- Using Phexxi as a contraceptive during the collection period of the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Queens Medical Center, 1004 Clinic POB1
Honolulu, Hawaii, United States, 96813
Actively Recruiting
Research Team
O
Olivia H Manayan, MD, MPH
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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