Actively Recruiting

Age: 18Years +
All Genders
ID07343167

Factors Associated With Mortality in Streptococcal Anginosus Bacteremia

Led by University Hospital, Strasbourg, France · Updated on 2026-01-15

400

Participants Needed

1

Research Sites

1 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating factors linked to mortality in infections caused by Streptococcal anginosus group bacteria, including S. constellatus, S. anginosus, and S. intermedius. These infections are known for their severity, high mortality rates estimated around 15%, and frequent infectious complications. The study aims to better understand what contributes to death in patients with these bloodstream infections. This is an observational study that looks at patients hospitalized with confirmed Streptococcal anginosus bacteremia. There are no treatments or interventions assigned by the study. Instead, researchers will collect and analyze data from patients who had positive blood cultures for these bacteria during the study period from January 1, 2019, through December 31, 2024. Participants will be adults 18 years or older who were hospitalized in participating centers and had at least one positive blood culture for the target bacteria. The main outcome measured is the 28-day in-hospital mortality following infection. The study will review medical records and laboratory results to identify factors associated with mortality. The research is sponsored by the University Hospital, Strasbourg, France, and the study is planned to end in March 2027.

CONDITIONS

Brief Title

Factors Associated With Mortality in Streptococcal Anginosus Bacteremia

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Hospitalized between January 1, 2019, and December 31, 2024, in a participating center
  • At least one positive blood culture for Streptococcus anginosus, Streptococcus constellatus, or Streptococcus intermedius during the study period
Not Eligible

You will not qualify if you...

  • Refusal to participate in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surveillance

Duration - 28 days

Participants who undergo routine care are observed for 28 days following their streptococcal infection to assess mortality outcomes.

Follow-up during hospitalization as per routine care

Trial Site Locations

Total: 1 location

1

Centre de référence des maladies vectorielles à tiques, CNR Borrelia - CHU de Strasbourg - France

Strasbourg, France, 67091

Actively Recruiting

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Research Team

V

Victor GERBER, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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