Falls in older adults with multiple myeloma.
Tanya M Wildes, Mark A Fiala
https://pubmed.ncbi.nlm.nih.gov/29239009Actively Recruiting
Phase Not Applicable
Age: 18Years +
All Genders
ID07044427
Investigation of Fall Risk Factors and Implementation of an Exercise Intervention for Prevention of Falls in Patients With Multiple Myeloma
Led by University Hospital Heidelberg · Updated on 2026-01-22
60
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University Hospital Heidelberg
Lead Sponsor
B
Bethanien Krankenhaus gGmbH
Collaborating Sponsor
AI-Summary
What this Trial Is About
Falls are a common issue for people over 65 years old, especially those with tumor diseases like multiple myeloma. These falls can lead to lower quality of life, reduced physical ability, and loss of independence, yet detailed scientific study on falls in cancer patients is limited. This research aims to identify fall risk factors in multiple myeloma patients and develop a structured exercise program to reduce fall risks and related injuries. Participants will receive a personalized home-based training plan that includes strength and balance exercises to be done three times a week for six months. Additionally, treadmill-based perturbation training will be provided at two specific times during the study. This intervention is designed to help prevent falls by improving physical stability. During the study, participants will be monitored for their ability to complete at least 48 of 72 training sessions focused on fall prevention over 24 weeks. Researchers will assess the fear of falling at the start and end of the six-month study. Participants will attend follow-up visits and complete questionnaires in German to evaluate the effectiveness and feasibility of the exercise program.
CONDITIONS
Brief Title
Fall Risk Assessment and an Exercise Intervention for Prevention of Falls in Multiple Myeloma Patients
Who Can Participate
Age: 18Years +
All Genders
Eligibility Criteria
You may qualify if you...
- Patients diagnosed with multiple myeloma requiring at least 6 months of systemic therapy
- ECOG performance status of 3 or less
- Age 18 years or older
- Willingness to perform the training program at least three times per week and attend planned follow-up visits
- Ability to give informed consent
- Written consent to participate in the study
- Sufficient German language skills to complete questionnaires
You will not qualify if you...
- Any physical or mental limitations that prevent participation in the training program or follow-up assessments
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
1
2
3
Your Study Journey
Screening
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Exercise Intervention
Duration - 6 months
Participants follow a personalized home-based training plan with strength and balance exercises carried out three times a week for six months. Additionally, treadmill-based perturbation training is performed at 2 timepoints.
2 visits for treadmill-based perturbation training; home exercises performed regularly
Trial Site Locations
Total: 1 location
1
University Hospital Heidelberg
Heidelberg, Baden Würtemberg, Germany, 69120
Actively Recruiting
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Research Team
U
Ulrike Dapunt, prof. Dr. med
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
PREVENTION
Number of Arms
1
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Published Research Related To This Trial
Systematic review of falls in older adults with cancer.
Tanya M Wildes, Priya Dua, Susan A Fowler...
https://pubmed.ncbi.nlm.nih.gov/25454770A precision-based exercise program for patients with multiple myeloma.
Ulrike Dapunt, Pauline Ehret, Jean-Luc Paratte...
https://pubmed.ncbi.nlm.nih.gov/37727991Falls in older adults with cancer: a systematic review of prevalence, injurious falls, and impact on cancer treatment.
Schroder Sattar, Shabbir M H Alibhai, Sandra L Spoelstra...
https://pubmed.ncbi.nlm.nih.gov/27450557Association of falls with health-related quality of life (HRQOL) in older cancer survivors: A population based study.
Chintan Pandya, Allison Magnuson, William Dale...
https://pubmed.ncbi.nlm.nih.gov/26907564