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Early Phase 1
Age: 18Years +
All Genders
ID07628634

Pilot Study of a Methionine-Reduced Diet in Adults With Solid Tumors Receiving Standard Cancer Treatment

Led by University of California, Irvine · Updated on 2026-07-31

25

Participants Needed

1

Research Sites

52 weeks

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the feasibility of a methionine-reduced diet and its effect on blood serum levels in adults with solid tumors who will also receive standard cancer treatments. This early phase 1 study focuses on supportive care to understand how well patients can follow this diet alongside their usual cancer therapy. Participants will follow a normal diet on days 1 to 3 and day 8, and a methionine-reduced diet from days 4 to 7. Standard systemic cancer treatment begins on day 8. The study looks at patient adherence over 8 days and monitors safety, biomarker changes, and quality of life over 43 days. Participants will be observed for adherence to the diet, safety, and biomarker changes through laboratory tests and questionnaires. Quality of life assessments will occur during the diet period. The total participation spans at least 43 days, during which researchers will measure how well the diet is tolerated and its impact on biomarkers and patient well-being.

CONDITIONS

Brief Title

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

Research Team

C

Chao Family Comprehensive Cancer Center University of California, Irvine

U

University of California Irvine Medical

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