Actively Recruiting
Florbetaben for Imaging of Vascular Amyloid
Led by Ottawa Heart Institute Research Corporation · Updated on 2026-05-08
30
Participants Needed
1
Research Sites
146 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The Primary Objective is to determine if a new nuclear tracer (named 18F-Florbetaben) used with nuclear imaging (PET imaging) can detect inflamed plaque in patients with recent ACS or stroke/TIA.
CONDITIONS
Official Title
Florbetaben for Imaging of Vascular Amyloid
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Suffered a recent cardiovascular event 30 to 120 days ago, such as ACS (STEMI or NSTEMI) or TIA/stroke with confirmed large vessel atherosclerotic disease
- Have stable symptoms and stable heart and blood circulation function
- Are 18 years of age or older
- Have given informed consent to participate
You will not qualify if you...
- Recent cardiovascular event that is likely embolic as judged by a neurologist or cardiologist
- Severe left ventricular dysfunction with ejection fraction less than 30%
- Severe valve disease that requires medical intervention
- Decompensated heart failure
- Pregnancy or breastfeeding
- Women who can have children but refuse to use two forms of contraception during the study, or men who can father children but refuse contraception
- Unable to provide informed consent
- Allergy to Florbetaben
- Kidney function with glomerular filtration rate less than 50 ml/min/1.72m2
- For CT angiography part: allergy to contrast dye or kidney function with GFR less than 60 ml/min/1.72m2
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Ottawa Heart Institute
Ottawa, Ontario, Canada, K1Y 4W7
Actively Recruiting
Research Team
K
Kevin E Boczar, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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