Histochemical Analysis of Gallbladder Stones in Children and Correlation With Etiological Factors

What this Trial Is About

This research aims to study the relationship between causes of pediatric gallbladder stones and their analysis after surgery. It focuses on children under 18 years old who have symptomatic or certain asymptomatic gallbladder stones, including those with congenital hemolytic anemia or specific imaging findings. The study is prospective and will take place from October 2024 to August 2025 at Sohag University Hospital's Department of Pediatric Surgery. Children in this study will undergo cholecystectomy, which is the surgical removal of the gallbladder, followed by histochemical analysis of their gallbladder stones. The study will investigate how different causes relate to the stone composition after this surgical procedure. There are no comparison groups or placebo treatments, and the study involves only this intervention. Participants will be followed up early, about one week after the operation, to detect the cause of their gallbladder stones. The study involves monitoring symptoms such as biliary colic, fever, vomiting, and imaging measurements like gallbladder thickness. Data collected will help understand the etiology of stones in children. The total study duration spans approximately 10 months, with ongoing evaluations and no mention of long-term follow-up beyond the initial postoperative period.

Gallbladder Stones in Children and Correlation With Etiological Factors