Comparing Depression Severity, Gender-Specific Symptoms, Resilience, and Stigma in Adults With Major Depressive Disorder

What this Trial Is About

Major Depressive Disorder MDD is a common and serious mental health condition that affects mood, thoughts, behavior, and overall quality of life. This research aims to compare women and men diagnosed with MDD by examining depression severity, gender-sensitive depressive symptoms, self-stigma, perceived social stigma, and psychological resilience. The study seeks to better understand how gender differences influence the experience and management of depression, with the goal of informing more personalized mental health care. The study involves two groups of participants women and men aged 18 to 65 years who have been diagnosed with MDD. Participants will be assessed at a single time point to evaluate various factors related to their depression, including the severity of symptoms and experiences of stigma and resilience. There are no interventions or treatments being tested in this observational study. Participants will complete assessments measuring depression severity, gender-sensitive depressive symptoms, self-stigma, perceived social stigma related to seeking psychological help, and psychological resilience. These evaluations will help researchers understand the relationships among these factors and how they differ between men and women. The total participation involves one baseline assessment during the study period ending in November 2026.

Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder