Actively Recruiting

Age: 18Years - 65Years
All Genders
ID07474363

A Comparative Examination of Depression Severity, Gender-Sensitive Depressive Symptoms, Psychological Resilience, and Stigma Levels in Women and Men With Major Depressive Disorder

Led by Eskisehir Osmangazi University · Updated on 2026-03-25

90

Participants Needed

1

Research Sites

30 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Major Depressive Disorder (MDD) is a common and serious mental health condition that affects mood, thoughts, behavior, and overall quality of life. This research aims to compare women and men diagnosed with MDD by examining depression severity, gender-sensitive depressive symptoms, self-stigma, perceived social stigma, and psychological resilience. The study seeks to better understand how gender differences influence the experience and management of depression, with the goal of informing more personalized mental health care. The study involves two groups of participants: women and men aged 18 to 65 years who have been diagnosed with MDD. Participants will be assessed at a single time point to evaluate various factors related to their depression, including the severity of symptoms and experiences of stigma and resilience. There are no interventions or treatments being tested in this observational study. Participants will complete assessments measuring depression severity, gender-sensitive depressive symptoms, self-stigma, perceived social stigma related to seeking psychological help, and psychological resilience. These evaluations will help researchers understand the relationships among these factors and how they differ between men and women. The total participation involves one baseline assessment during the study period ending in November 2026.

CONDITIONS

Brief Title

Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Male and female patients aged 18 to 65 years
  • Diagnosis of Major Depressive Disorder according to DSM-5 at the time of study participation
  • Provision of voluntary informed consent
Not Eligible

You will not qualify if you...

  • Intellectual disability
  • Severe neurological disorders
  • Comorbid psychiatric diagnoses
  • Depressive disorder secondary to an organic medical condition
  • Depressive disorder secondary to substance use

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Single assessment at baseline

Participants complete assessments measuring depression severity, gender-sensitive depressive symptoms, self-stigma, social stigma, and psychological resilience.

1 visit (in-person)

Long-term Monitoring

Duration - Up to study completion in November 2026

Participants are observed following initial assessments without active intervention.

Visits as per routine clinical care

Trial Site Locations

Total: 1 location

1

the Department of Psychiatry Outpatient Clinic at Eskişehir Osmangazi University Faculty of Medicine

Eskişehir, Eskişehir, Turkey (Türkiye), 26040

Actively Recruiting

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Research Team

İ

İrem OZKAYNAK DAGLİ, Research assistant, M.D.

H

HARUN O SONKURT, Asst. Prof.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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