Actively Recruiting
Clinical Investigation of Genetic Markers in Diabetic Ulcers and Their Role in Personalized Treatment Targeting
Led by The First Affiliated Hospital of University of South China · Updated on 2025-05-18
712
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying genetic markers in patients with diabetic ulcers to better understand the risk factors and healing differences related to these ulcers. The study aims to integrate various multi-omics data to create a risk prediction model for diabetic ulcers. By focusing on specific genetic variations and their pathways, the research seeks to identify potential new drug targets that could help promote healing and provide a foundation for personalized treatments. The study involves collecting samples of peripheral blood, ulcer tissue, and fecal matter from participants with diabetic ulcers. These samples will be analyzed using bioinformatics techniques to identify genetic markers associated with ulcer risk and healing. The research will explore these markers and their regulatory pathways to develop targeted treatment options. This is an observational study without drug or device interventions. Participants will be monitored over three years, during which researchers will assess several outcomes including ulcer healing time, changes in ulcer size, number of amputations, ulcer recurrence, wound closure time, foot infections, quality of life, and length of hospital stays. The study involves ongoing observation and data collection to understand the progression and potential treatment targets for diabetic ulcers.
CONDITIONS
Brief Title
Genetic Markers of Diabetic Ulcers and Personalized Treatment Targets Research
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Voluntarily agree to participate and sign informed consent
- Have type 2 diabetes and diabetic ulcers
- Have had diabetes for 10 years or more, or be 55 years or older at enrollment
- Be an inpatient or outpatient who can be monitored by the same medical team throughout the study
You will not qualify if you...
- Have severe vascular blockage or impairment
- Have congenital heart disease, aortic dissection, or other serious cardiovascular diseases
- Have ulcers caused by factors other than diabetes
- Have severe liver or kidney dysfunction or serious neurological damage
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 3 years
Participants are observed over time to monitor ulcer healing, recurrence, infections, and other health outcomes related to diabetic ulcers.
Regular visits with the same medical team throughout the study
Trial Site Locations
Total: 1 location
1
The First Affiliated Hospital of University of South China
Hengyang, Hunan, China, 421001
Actively Recruiting
Research Team
J
Jiecan Zhou, Prof.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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