Actively Recruiting

Age: 1Year - 100Years
All Genders
ID03381794

Trends in Corneal Transplantation From 2001 in Germany: Reports of the DOG-Section Cornea and Its Keratoplasty Registry

Led by Universität des Saarlandes · Updated on 2026-04-27

100000

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

Sponsors

U

Universität des Saarlandes

Lead Sponsor

U

University Eye Hospital, Freiburg

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are studying the trends in corneal transplantation procedures performed in Germany since 2001. This observational study aims to provide regular updates on the number of surgeries, the types of surgical techniques used, and the reasons for these corneal transplants. The German Ophthalmological Society's Section Cornea oversees this long-term registry to track and report these changes. The study involves all patients in Germany who have undergone various types of corneal transplantation procedures, including Penetrating Keratoplasty (PKP), Deep Anterior Lamellar Keratoplasty (DALK), Descemet Membrane Endothelial Keratoplasty (DMEK), and Descemet's Stripping Automated Endothelial Keratoplasty (DSAEK). These procedures are observed and documented to understand evolving surgical practices and patient indications. Participants' data are collected continuously from 2001 through 2031, monitoring the absolute numbers of corneal transplants, the trends in different surgical types, and the medical reasons for transplantation. The registry provides interim assessments to keep current with the latest results, aiming for comprehensive long-term insight into corneal transplantation patterns in Germany.

CONDITIONS

Brief Title

The German Keratoplasty Registry of the German Ophthalmological Society (DOG)

Who Can Participate

Age: 1Year - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients in Germany treated with any type of corneal transplantation since 2001.
Not Eligible

You will not qualify if you...

  • Patients without corneal transplantation.

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - Varies depending on procedure and recovery

Participants undergo corneal transplantation procedures including PKP, DALK, DMEK, or DSAEK.

1 visit for the transplantation procedure

Long-term Monitoring

Duration - From 2001 to 2031

Participants who have undergone corneal transplantation are observed to report on trends, indications, and outcomes over time.

Follow-up visits as per routine care and registry data collection

Trial Site Locations

Total: 1 location

1

Department of Ophthalmology

Homburg, Saarland, Germany, 66421

Actively Recruiting

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Research Team

E

Elias Flockerzi, PD Dr.med.

B

Berthold Seitz, Prof.Dr.med.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Published Research Related To This Trial

Descemet's membrane endothelial keratoplasty is the predominant keratoplasty procedure in Germany since 2016: a report of the DOG-section cornea and its keratoplasty registry.

Elias Flockerzi, Christina Turner, Berthold Seitz...

https://pubmed.ncbi.nlm.nih.gov/37586835

Trends in Corneal Transplantation from 2001 to 2016 in Germany: A Report of the DOG-Section Cornea and its Keratoplasty Registry.

Elias Flockerzi, Philip Maier, Daniel Böhringer...

https://pubmed.ncbi.nlm.nih.gov/29410297