Actively Recruiting
Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer
Led by University Medical Center Groningen · Updated on 2025-01-01
300
Participants Needed
10
Research Sites
277 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
In this study the characteristics and alterations of the gut microbiome during chemotherapy for metastasized or irresectable CRC are studied, as well as the relation between the gut microbiome and the effects of chemotherapy.
CONDITIONS
Official Title
Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age �3E�3D 18 years
- Histologically confirmed colorectal cancer with indication for palliative systemic anti-tumor therapy
- Measurable disease according to RECIST v1.1
- Stored pathological specimens available
- Life expectancy of at least 12 weeks
- Signed informed consent form
- Ability to comply with study protocol
You will not qualify if you...
- Previous (neo)adjuvant chemotherapy within the last 6 months
- Previous radiotherapy on the small or large intestine within the last month
- Previous surgery of the small or large intestine within the last month
- Uncontrolled inflammatory bowel disease
- Participation in a study that may affect the gut microbiome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 10 locations
1
Wilhelmina Ziekenhuis
Assen, Netherlands
Actively Recruiting
2
Ziekenhuis Nij Smellinghe
Drachten, Netherlands
Actively Recruiting
3
Treant Zorggroep
Emmen, Netherlands
Actively Recruiting
4
Medisch Spectrum Twente
Enschede, Netherlands
Actively Recruiting
5
University Medical Center Groningen
Groningen, Netherlands, 9713 GZ
Actively Recruiting
6
Martini Ziekenhuis
Groningen, Netherlands
Actively Recruiting
7
Tjongerschans Ziekenhuis
Heerenveen, Netherlands
Actively Recruiting
8
Medisch Centrum Leeuwarden
Leeuwarden, Netherlands
Actively Recruiting
9
Ommelander Ziekenhuis Groep
Scheemda, Netherlands
Actively Recruiting
10
Antonius Zorggroep
Sneek, Netherlands
Actively Recruiting
Research Team
J
J. J. de Haan, MD, PhD
CONTACT
D
D. J. de Groot, MD, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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