Study Comparing Blood Markers MPV, PLR, and NLR in Primary and Secondary Antiphospholipid Syndrome

What this Trial Is About

Antiphospholipid syndrome APS is an autoimmune disorder characterized by blood clots and pregnancy complications, with varied clinical presentations. It can occur as a primary condition or secondary to other autoimmune diseases like systemic lupus erythematosus. This research evaluates blood markers linked to inflammation and immune response, including mean platelet volume MPV, platelet-to-lymphocyte ratio PLR, and neutrophil-to-lymphocyte ratio NLR, in primary versus secondary APS cases. Participants undergo diagnostic tests such as complete blood counts to measure MPV, PLR, and NLR, along with assessments of antiphospholipid antibody profiles. These blood markers are studied for their potential to reflect inflammation and platelet activity related to APS. The study compares these markers between primary APS and secondary APS groups to understand differences in disease processes. During the study, participants provide blood samples for analysis of these hematological markers. Researchers will evaluate baseline measurements of MPV, PLR, and NLR in both APS types. The study monitors these markers to explore their role in APS diagnosis and prognosis. Participation involves blood testing without active treatment, and the study duration covers from screening through baseline assessments.

Hematological Markers MPV, PLR, and NLR in Primary Versus Secondary Antiphospholipid Syndrome