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High Frequency Visual Stimulation to Improve Thinking, Movement, and Mood in Older Adults With or Without Subjective Cognitive Decline
Led by University of Florida · Updated on 2026-08-03
60
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating whether sensory flicker stimulation performed at least three times a week for three months can improve thinking skills, movement, and mood in healthy older adults and those with subjective cognitive decline SCD. They aim to see if this intervention slows brain changes linked to Alzheimers disease, including cortical thinning and changes in brain network function and blood biomarkers. Participants are randomly assigned to one of two groups. One group will wear visual occlusion glasses delivering stimulation at a slower rate of 1 Hz control, while the other group will receive stimulation at a faster rate of 16.67 Hz experimental. The intervention lasts three months with assessments at the start, halfway point 1.5 months, and at the end. During the study, participants undergo cognitive tests, mobility evaluations like grip strength and walking speed, mood questionnaires, and brain imaging to measure structure and function. Blood tests will track Alzheimers-related biomarkers. These evaluations occur at baseline, midway, and after the intervention. The total participation duration is about three months, with ongoing monitoring of safety and adherence.
CONDITIONS
Brief Title
High Frequency Stimulation to Improve Cognition, Mobility, and Affect in Individuals With and Without Subjective Cognitive Decline
Research Team
A
Alyssa Hayes
S
Sarah Verdecia-Zabala
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