The HOTSPOT Study Hybrid Implementation-effectiveness Study to Optimize HIV Testing and PrEP in a Southern Jail

What this Trial Is About

This research aims to evaluate a multicomponent strategy to support pre-exposure prophylaxis (PrEP) for people incarcerated at the Dallas County Jail. The study focuses on identifying individuals at higher risk of HIV using an electronic medical record prediction model, provider referrals, or self-referrals. The goal is to measure how well this approach works to implement PrEP and related clinical outcomes, including HIV and STI testing and diagnoses, across the jail-to-community transition. The study involves a single group where eligible participants at the Dallas County Jail receive a PrEP navigation visit. During this visit, a PrEP patient navigator discusses HIV risk, offers HIV and STI testing if not already done, provides education about PrEP, and refers individuals to community-based PrEP providers after release. The study uses mixed methods and the EPIS framework to assess the process and impact of this strategy. Participants will be monitored for their linkage to PrEP care within 90 days after release from jail. Researchers will collect data through quantitative and qualitative assessments throughout the study period, which runs from March 2025 to August 2027. The study includes evaluations of HIV/STI testing, diagnoses, and PrEP uptake, aiming to define an effective and acceptable PrEP implementation method for jails.

HOTSPOT Study: Implement and Evaluate the PrEP (Pre-exposure Prophylaxis) Implementation Strategy