Actively Recruiting

Age: 18Years +
All Genders
NCT06489665

Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective Study

Led by University of Zurich · Updated on 2025-02-05

350

Participants Needed

2

Research Sites

306 weeks

Total Duration

On this page

Sponsors

U

University of Zurich

Lead Sponsor

C

Center for Proton Therapy, Paul Scherrer Institute, Villigen,Switzerland

Collaborating Sponsor

AI-Summary

What this Trial Is About

Conventional mammography, breast sonography and breast MRI have specific weaknesses. In particular, mammography has a low sensitivity for the detection of mammary carcinoma in patients with a dense breast. Phase contrast mammography could help to overcome some of these limitations. Observational study.

CONDITIONS

Official Title

Imaging Quality and Potential Clinical Relevance of Phase Contrast Mammography In-vivo: a Single-center, Prospective Study

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Phase 0: Over 18 years old
  • Phase 0: Scheduled for mastectomy, tumorectomy, or biopsy
  • Phase 0: Provided informed consent
  • Phase 1: Over 18 years old
  • Phase 1: BI-RADS 5 or 6 breast cancer diagnosis
  • Phase 1: Scheduled for mastectomy or breast conserving surgery with radiotherapy
  • Phase 1: Provided informed consent
  • Phase 2: Over 40 years old
  • Phase 2: Undergoing mammography for screening or diagnosis
  • Phase 2: Provided informed consent
Not Eligible

You will not qualify if you...

  • Presence of breast implants
  • Unable to understand study procedures due to cognitive or language difficulties
  • Pregnant or breastfeeding (Phase 1 and 2 participants)
  • Re-staging after neoadjuvant chemotherapy
  • Participation in research involving ionizing radiation within past 12 months (Phase 1 and 2)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University Hospital Zurich - Diagnostic Radiology

Zurich, Canton of Zurich, Switzerland, 8091

Actively Recruiting

2

University of Zurich

Zurich, Switzerland

Actively Recruiting

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Research Team

T

Thomas Frauenfelder, Prof

CONTACT

J

Judith Jehle

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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