Actively Recruiting
Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP)
Led by University Hospital, Rouen · Updated on 2026-05-04
44
Participants Needed
1
Research Sites
261 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The general objective of the proposed project is to characterise phenotypically and functionally ADAMTS13-specific memory B lymphocytes and autoreactive T lymphocytes, in particular follicular helper T lymphocytes, in the acute phase of the disease, but also during its progression after treatment. The aim is to highlight their contribution to the initial pathogenic process, their evolution under treatment, and also their involvement in patients who are refractory to immunosuppressive therapies and during relapses. The aim of this project is to identify early phenotypic or functional parameters that are predictive of relapse and that can be used for personalised optimisation of treatment to maintain remission.
CONDITIONS
Official Title
Immunological Aspect of Thrombotic Thrombocytopenic Purpura (TTP)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18
- Patients diagnosed with TTP at any stage (acute, remission, or relapse)
- Receiving care in internal medicine at Rouen University Hospital
- Have read and understood the study information letter
- Member of a social security scheme
You will not qualify if you...
- Currently deprived of liberty by administrative or judicial decision
- Under court protection, guardianship, or similar legal supervision
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Rouen Hospital,
Rouen, France, 76031
Actively Recruiting
Research Team
D
David DM MALLET, Director
CONTACT
V
Vincent VF FERRANTI, ARC
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
4
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here