Actively Recruiting
Impact of Dapagliflozin in Anemic Chronic Kidney Disease Patients
Led by Mansoura University · Updated on 2025-04-02
80
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Dapagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor, primarily used in the management of type 2 diabetes mellitus. Emerging research suggests that SGLT2 inhibitors may offer additional benefits, including reducing the risk of cardiovascular events and renal complications. Post hoc analyses of previous clinical trials have shown that patients treated with SGLT2 inhibitors exhibited higher levels of hemoglobin and hematocrit compared to those in the control group. These findings suggest that dapagliflozin's ability to elevate hemoglobin levels could potentially be utilized for the treatment of anemia in patients with chronic kidney disease.
CONDITIONS
Official Title
Impact of Dapagliflozin in Anemic Chronic Kidney Disease Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 65 18 years with CKD stage III or IV
- Anemia of CKD with hemoglobin level < 11.5 g/dL
- Receiving erythropoiesis-stimulating agent therapy
You will not qualify if you...
- Anemia due to causes other than chronic kidney disease, such as pernicious anemia, thalassemia, sickle cell anemia, or myelodysplastic syndromes
- Severe ketosis, diabetic coma, severe infection, perioperative complications, or severe trauma
- Acute heart failure, acute myocardial infarction, or stroke within 6 months before enrollment
- Current malignancies or history of malignancy within the past 2 years
- Diagnosed with pure red cell aplasia
- Severe gastrointestinal bleeding
- Pregnant or lactating females
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Urology and Nephrology Center
Al Mansurah, Egypt
Actively Recruiting
Research Team
B
Basma M. Sayed Ahmed, M.Sc.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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