What is this study trying to find out about obesity and overweight?

This study is examining how exercise affects physical fitness and blood components in adults who are overweight or obese. Researchers aim to gain new knowledge to help develop alternative treatments and health strategies. The study is sponsored by Mahidol University and focuses on exercise's role in managing obesity-related health issues.

Who may be eligible for this obesity and overweight clinical trial?

Adults aged 25 to 45 years with a body mass index (BMI) between 25 and 35 kg/m² who are Thai nationals may be eligible. Participants should have low physical activity levels and be able to walk independently. People with certain medical conditions or who regularly exercise may not qualify. Please review eligibility criteria for more details.

Is there any cost to participate in this obesity and overweight clinical trial?

Study-related care, including the exercise program and all trial visits, is provided at no cost. However, personal travel expenses to attend study visits may vary and are not guaranteed to be covered. Participants should plan accordingly for transportation costs.

Actively Recruiting

Phase Not Applicable

Age: 25Years - 45Years

All Genders

ID07312344

Study of High-Intensity Interval Training Effects on Blood and Physical Fitness in Overweight and Obese Adults Aged 25-45

Led by Mahidol University · Updated on 2025-12-31

Participants Needed

Research Sites

N/A

Total Duration

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of exercise on physical fitness and blood components in adults who are overweight or obese. This study aims to provide new insights that could help medical professionals, researchers, and companies develop alternative treatments and health promotion strategies to delay or prevent obesity-related diseases. The research focuses on changes in physical fitness and blood markers before and after exercise intervention. Participants will take part in a high-intensity interval training HIIT program conducted on a treadmill at 65% to 80% of their maximum heart rate. The exercise sessions occur three times a week for six weeks. This intervention is designed to assess how exercise influences blood components and various measures of physical fitness. During the study, participants will undergo multiple assessments including blood tests, foot pressure distribution analysis, facial and abdominal fat thickness measurements, VO2max testing, body composition analysis, heart rate monitoring, grip and leg strength tests, body weight, and height measurements. These evaluations happen before starting the exercise program and after completing it. The study monitors changes to understand the impact of exercise on overweight and obese individuals.

CONDITIONS

Brief Title

Impact of Exercise-derived Extracellular Vesicle in Blood and Physical Fitness Data in Overweight/Obesity Individuals

Who Can Participate

Age: 25Years - 45Years

All Genders

Eligibility Criteria

You may qualify if you...

Male or female individuals aged between 25-45 years
Thai nationality
Ability to walk or perform daily activities independently without assistive devices
Body mass index (BMI) between 25-35 kg/m²
Low physical activity level or sedentary lifestyle, with moderate-intensity activity less than 150-300 minutes per week or vigorous-intensity activity less than 75-150 minutes per week

You will not qualify if you...

Smoking, substance abuse, or alcohol addiction
History of respiratory diseases such as asthma, emphysema, or chronic obstructive pulmonary disease
History of cardiovascular diseases such as coronary heart disease, aortic disease, arrhythmia, or deep vein thrombosis
History of high blood pressure (hypertension)
History of vestibular system diseases such as Meniere's disease or otitis media
History of neurological diseases such as severe Parkinson's disease or stroke
History of previous lower limb surgery such as hip, knee, or ankle replacement
History of musculoskeletal diseases such as severe osteoarthritis
History of severe brain diseases such as dementia
Severe visual or hearing impairment
Cognitive and comprehensive impairment preventing completion of the intervention
Regular high physical activity or exercise

Research Team

Onaong Mee-inta, Ph.D.

Phunsuk Kantha, Ph.D.

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Study of High-Intensity Interval Training Effects on Blood and Physical Fitness in Overweight and Obese Adults Aged 25-45

On this page

AI-Summary

What this Trial Is About

Brief Title

Who Can Participate

Eligibility Criteria

Research Team

Not the Right Trial for You?

On this page

Who Can Participate

Eligibility Criteria