Study of Changes in Redox Potential During Cardiac Bypass Surgery and Their Link to Recovery

What this Trial Is About

This observational study is conducted at a single center in the cardiac surgery department to investigate biological markers that may predict the short-term outcomes of patients undergoing heart surgery. The study focuses on redox balance, which is the interaction between oxidants and reducers in tissues, a key factor in regulating cellular functions. Cardiac surgery involving extracorporeal circulation causes major disturbances in this balance, and early findings suggest that changes in redox potential could be linked to post-operative complications, potentially serving as a new biomarker. Participants are scheduled for cardiac bypass surgery with saphenous vein harvesting. Blood samples will be collected from catheters used during surgery or routine venipuncture before the operation, and tissue samples will be taken from surgical waste without additional procedures. Additionally, participants will complete a walking test between days 5 and 7 after surgery to assess recovery. Throughout the study, researchers will measure the Simplified Gravity Index on day 7 to evaluate the post-operative outcome. Participants will be observed for biological marker changes and recovery progress. The involvement includes sample collections and the walking test, with no investigational treatments administered. The study lasts through the immediate post-operative period until day 7, focusing on short-term outcome monitoring.

Impact of VARIation of OXYdo-reduction Potential in Cardiac Surgery on Post-operative Outcome