Effect of a Multidisciplinary Lifestyle Intervention on the Exposome of Premenopausal Women with Stage I-III Breast Cancer

What this Trial Is About

Breast cancer is a leading cause of death among women worldwide, especially in Latin America, where younger women are often diagnosed at advanced stages with aggressive tumor types. Lifestyle factors, including diet, physical activity, and psychological stress, influence the internal and external exposome, which impacts breast cancer development and treatment outcomes. This study evaluates how a multidisciplinary lifestyle intervention might affect the personal exposome and health of young women with breast cancer. The trial compares two groups: one receives a hybrid multidisciplinary lifestyle education program delivered through digital tools and face-to-face sessions, while the other receives a personalized hybrid multidisciplinary intervention tailored to clinical evaluations and includes nutritional, psychological, rehabilitation, and mindfulness support. Both groups use digital platforms like apps, workshops, and videos for education and motivational support, with follow-up through various communication methods. Participants will be involved for 18 months, undergoing assessments at baseline and at multiple intervals to measure lifestyle adoption, physical activity, sleep quality, anxiety, depression, mindfulness, body composition, and biochemical markers. Researchers will track adherence through attendance and questionnaires, evaluating quality of life and barriers to lifestyle changes. This comprehensive approach aims to understand how early intervention may improve metabolic control, clinical outcomes, and overall well-being in young breast cancer patients.

Improving Lifestyle Behavior by "Joven, Fuerte y Saludable" Multidisciplinary Program.