Study on Development and Sensory Skills in Infants Aged 6 to 18 Months With Primary Congenital Hypothyroidism

What this Trial Is About

Researchers are studying infants aged 6 to 18 months with primary congenital hypothyroidism, a condition where the thyroid gland is underactive or absent. This condition can affect brain development, leading to cognitive and motor challenges despite early hormone treatment. The study aims to explore neurological status, motor skills, and sensory processing abilities during this critical early stage of brain development called synaptogenesis. The goal is to better understand how congenital hypothyroidism impacts these developmental areas to support early follow-up and intervention. The study compares infants diagnosed and treated for primary congenital hypothyroidism with a control group of healthy infants born at term. Assessments include the Hammersmith Infant Neurological Examination to evaluate neurological status, the Test of Sensory Function in Infants to assess sensory processing, and the Peabody Developmental Motor Scales-2 to measure motor development. These tests are standardized and designed for infants within the studys age range. Participants will undergo developmental and neurological evaluations between 6 and 18 months of age. Researchers will collect data on motor skills, sensory abilities, and neurological health through these assessments. The study may help establish scientific evidence for early monitoring and intervention programs. The total participation period aligns with the infants ages from 6 to 18 months, focusing on early detection of developmental differences.

Infants With Primary Congenital Hypothyroidism and Development