Actively Recruiting

Age: 18Years - 40Years
All Genders
Healthy Volunteers
NCT06478303

LAnguage-Motor Imagery Circuits to Improve Motor Learning and Language Comprehension

Led by University Hospital, Grenoble · Updated on 2024-08-02

105

Participants Needed

2

Research Sites

208 weeks

Total Duration

On this page

Sponsors

U

University Hospital, Grenoble

Lead Sponsor

U

University of Burgundy

Collaborating Sponsor

AI-Summary

What this Trial Is About

Recent evidence suggests that cognitive systems do not operate in isolation but interact within broader networks, thus opening new avenues for fundamental and clinical research. An illustrative example is the interaction between language comprehension and motor representations. For instance, motor training (e.g., sports, origami training) can facilitate action verb recognition, whereas motor deficits (e.g., upper limb immobilization) can hinder the processing of action language. Similarly, action language has been shown to affect motor performance. These effects are attributed to an implicit form of motor imagery, an automatic simulation of motor experience (without actual movement) evoked by action words. Interestingly, literature supports the idea that the motor simulations used for imagining an action are also engaged during the reading of action language, leading to similar neurophysiological and behavioral changes in both processes. However, questions remain about the similarity of the simulations generated by motor imagery and action language. This project, encompassing three experimental sequences, aims to address these questions to achieve significant scientific advancements in both theoretical and applied domains.

CONDITIONS

Official Title

LAnguage-Motor Imagery Circuits to Improve Motor Learning and Language Comprehension

Who Can Participate

Age: 18Years - 40Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Persons who have given written consent
  • Healthy subjects
  • Subjects reading and understanding French
  • Right-handed
  • Affiliated with a social security system
  • Between 18 and 40 years old
  • Completed the TMS inclusion questionnaire or had a medical examination before MRI study participation
Not Eligible

You will not qualify if you...

  • Severe general medical conditions: cardiac, respiratory, hematological, renal, hepatic, cancerous
  • Regular use of anxiolytics, sedatives, antidepressants, neuroleptics
  • Characterized psychiatric pathology
  • Ingestion of alcohol prior to examination
  • Persons covered by articles L1121-5 to L1121-8 of the CSP
  • Presence of contraindications to MRI or TMS

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 2 locations

1

CHU Grenoble Alpes

Grenoble, Grenob, France, 38043

Actively Recruiting

2

Université de Bourgogne

Dijon, France

Actively Recruiting

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Research Team

L

Laurent VERCUEIL

CONTACT

W

William DUPONT

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

5

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