Ain Taya

Researchers are studying the outcomes of pregnancies that happened before the diagnosis of systemic lupus erythematosus (SLE) in women who were later diagnosed with this condition. The study focuses on understanding maternal and fetal health during these pregnancies and examining signs of SLE that may have been present before or during pregnancy. It also aims to assess how severe the disease was at the time it was diagnosed using standard criteria. The study collects information from medical records and patient interviews, focusing on all pregnancies before and after the SLE diagnosis. For living participants, data is gathered through questionnaires about obstetrical events prior to diagnosis. For deceased patients, medical records are reviewed. Researchers will also collect available data on body measurements, biological, immunological, and kidney tissue findings before and after diagnosis. Disease activity and severity after diagnosis will be assessed using recommended tools. Participants will be evaluated from the start of each pregnancy and followed up to three months after childbirth. The study measures include the prevalence of pregnancy-related events before SLE diagnosis, severity of the disease at diagnosis, and pregnancy outcomes before and after SLE diagnosis. The study is observational and retrospective, focusing on collecting and analyzing past pregnancy and health information to better understand the relationship between pregnancy and SLE development.