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Study of Pregnancy Outcomes Before a Systemic Lupus Erythematosus Diagnosis Observing Maternal and Fetal Health in Women Diagnosed After Pregnancy
Led by University of Algiers · Updated on 2025-12-31
50
Participants Needed
2
Research Sites
17 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying pregnancies that occurred before the diagnosis of systemic lupus erythematosus SLE in women who were later diagnosed with this condition. This observational, retrospective cohort study aims to understand maternal and fetal outcomes as well as systemic signs of SLE present before or during pregnancy. The diagnosis of SLE is based on established criteria including the ACR 1997 and renal histological findings. The study collects information from medical records and patient interviews during medical visits. Data on all pregnancies before and after the diagnosis of SLE will be gathered, including obstetrical events and features such as anthropometric, biological, immunological, and histological data when available. The severity and activity of SLE after diagnosis will also be assessed using recommended tools. Participants will be evaluated from the beginning of each pregnancy until three months after childbirth. Researchers will measure the prevalence of obstetrical events before SLE diagnosis and compare pregnancy outcomes before and after diagnosis. The study involves reviewing medical histories and asking questions during visits to better understand how SLE affects pregnancies and disease severity over time.
CONDITIONS
Brief Title
Pregnancies Before the Diagnosis of Systemic Lupus Erythematosus
Research Team
W
Wafia- Nadia Nibouche - Hattab, Professor in medicine
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