Nova Itaberaba

Researchers are conducting a retrospective observational cohort study to evaluate clinical, pathological, and treatment data of people diagnosed with adrenocortical carcinoma since the year 2000. This rare cancer has a notably higher incidence in certain regions of Brazil, partly due to a common genetic mutation called TP53-R337H. The study aims to characterize this patient group and identify factors that influence outcomes, focusing on cases from major Brazilian treatment centers. Participants in this study are identified based on past clinical records rather than receiving new treatments. The study collects data from medical evaluations and follow-ups conducted at reference centers, including initial diagnosis and recurrences from 2000 onward. There are no interventions or experimental treatments given during this observational study. Participants involvement includes reviewing their medical history and clinical data over approximately 18 months. Researchers will analyze demographic and clinical characteristics from existing records to better understand the disease in this population. The study does not involve active treatment but focuses on data collection and analysis for improved knowledge of adrenocortical carcinoma in Brazil.