Nova Itaberaba

Adrenocortical carcinoma is a rare cancer, but in Brazil, particularly in the South and Southeast, its occurrence is about 15 times higher than in other parts of the world due to a common genetic mutation called TP53-R337H. This research aims to study the clinical and epidemiological characteristics of people diagnosed with this cancer in Brazil from the year 2000 onward, focusing on identifying factors that may influence patients' outcomes. The study builds on a previous group of 66 patients treated at a major cancer center and seeks to include additional cases from key Brazilian treatment sites. This is a retrospective observational cohort study, meaning researchers will review past medical records of patients diagnosed with adrenocortical carcinoma who received care at participating centers. The study does not involve new treatments or interventions but analyzes existing clinical, pathological, and treatment data. Participants are identified from records starting in 2000, and their information is collected to better understand the disease in this population. Participants' medical records will be examined for demographic details and clinical characteristics over an average follow-up period of 18 months. Researchers will evaluate clinical evaluations, pathology reports, and treatment data to characterize the disease and its progression. The study focuses on gathering information to improve knowledge about adrenocortical carcinoma in Brazil, with no active treatment or direct participant visits involved.