Klingenmunster

The German Dementia Registry DEMREG is a large-scale national study focused on collecting real-world data from patients diagnosed with Subjective Cognitive Decline SCD, Mild Cognitive Impairment MCI, and early dementia of various types in Germany. The study aims to follow patients over time to better understand the natural progression of dementia and differences between types such as Alzheimers and other dementias. It provides a clinical platform for research that aligns with current diagnostic and treatment guidelines. This is an observational registry study where no treatments are given as part of the research. Instead, patients usual care and medications are documented. Data are collected through patient visits using questionnaires and tests related to early dementia. The registry collects biomarker data, including cerebrospinal fluid and imaging markers, and follows patients annually for as long as possible to track changes over time. Participants will have baseline and yearly follow-up visits where clinical data, biomarker results, and questionnaire information are gathered. The study monitors the natural course of dementia and changes in biomarkers, aiming to inform future diagnostic criteria and treatment approaches. Participation involves consenting patients and optionally family members who are involved in the patients care. The registry is ongoing with long-term follow-up planned.