Klingenmunster

Researchers are conducting the German Dementia Registry (DEMREG), a large national study in Germany that collects ongoing data from patients diagnosed with cognitive issues such as Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI), and early dementia from various causes. This registry aims to gather real-world, long-term information aligned with clinical guidelines to better understand the natural progression of dementia and differentiate between types like Alzheimer's and other dementias. The study also seeks to track biomarker changes and treatment patterns in routine healthcare settings, which may improve early diagnosis and treatment approaches for dementia. This is an observational registry study where no treatments are provided as part of the research. Instead, the study documents patients' usual care and medications while collecting additional data through questionnaires and tests related to early dementia. Data collection occurs during patient visits using an online platform, integrating clinical routine procedures and biomarker measurements such as cerebrospinal fluid and imaging results. The registry follows patients prospectively over time to monitor disease progression and biomarker changes. Participants and their family members provide informed consent and contribute data at baseline visits, with follow-up visits occurring annually for as long as possible. The registry gathers comprehensive clinical, biomarker, and questionnaire data to analyze dementia's natural history and healthcare practices in Germany. This ongoing data collection supports better understanding and potential improvements in dementia diagnosis and care. There is no maximum age limit for participation, and the registry includes both patients and involved family members.